Understanding Blebs: Small Protrusions with Big Roles in Cell Signaling and Adhesion

Blebs are small, blister-like protrusions that can occur on the surface of cells. They are typically found in epithelial cells, which line the outer and inner surfaces of the body, and are thought to be involved in cell signaling and adhesion.

Blebs are formed when a cell's membrane folds inward to create a small pocket of cytoplasm that is not connected to the rest of the cell. This pocket can then fill with fluid, creating a blister-like structure that protrudes from the surface of the cell.

Blebs can serve a number of functions, including:

1. Cell signaling: Blebs can be used to transmit signals between cells, such as during cell adhesion and migration.
2. Adhesion: Blebs can help cells stick together and form tissues.
3. Mechanical stress: Blebs can help cells respond to mechanical stress, such as stretching or compression.
4. Cell movement: Blebs can help cells move and change shape, such as during cell migration and invasion.

Blebs are also involved in a number of diseases, including cancer, where they can contribute to the spread of cancer cells.