Understanding Keratoglobus: Causes, Symptoms, and Treatment Options

Keratoglobus is a rare genetic disorder that affects the development of the cornea, which is the clear outer layer of the eye. It is characterized by a thickening of the corneal stroma, which can lead to vision problems and other complications.

The symptoms of keratoglobus can vary depending on the severity of the condition, but may include:

* Blurred vision
* Double vision
* Sensitivity to light
* Eye pain or discomfort
* Redness or inflammation of the eye

Keratoglobus is caused by a mutation in the COL5A2 gene, which codes for a protein that is important for the structure and strength of the cornea. The condition is usually inherited in an autosomal dominant pattern, meaning that a single copy of the mutated gene is enough to cause the condition.

There is no cure for keratoglobus, but there are several treatment options available to help manage the symptoms and slow the progression of the condition. These may include:

* Glasses or contact lenses to correct vision problems
* Medications to reduce inflammation and pain
* Surgery to remove the cloudy corneal tissue
* Corneal transplantation in severe cases

It is important for individuals with keratoglobus to receive regular eye exams to monitor their condition and adjust their treatment as needed. With proper management, many people with keratoglobus are able to maintain good vision and lead active lives.